Sleep problems have become a common concern in modern society. With the accelerating pace of life, increasing work pressure and technological development, more and more Chinese people are facing the problem of declining sleep quality. According to the 2024 China Sleep Health White Paper by the China Sleep Research Society, only 19 percent of the population has no sleep disorders.

Why do sleep problems occur?

What are the effects of sleep deprivation on human health?

Can melatonin solve sleep problems at their root?

What is the relationship between NMN and circadian clock regulation?

The causes of sleep disorders

1. You don't get enough sleep

Many Chinese people can't get enough sleep due to work pressure, stressful life and other reasons. A survey shows that more than 60% of people sleep less than 7 hours a day, and even a significant number of people sleep less than 6 hours a day. Chronic sleep deprivation can lead to fatigue, poor concentration, memory loss and other problems.

2. Insomnia

Insomnia refers to problems such as difficulty falling asleep, poor sleep quality or waking up early. Many people have difficulty falling asleep at night or do not sleep deeply, resulting in low energy during the day. Insomnia problems may be related to stress, anxiety, depression and other factors. Survey data show that more than 30% of people have varying degrees of insomnia problems.

3. An irregular body clock

Many people have irregular daily routines, often staying up late, sleeping late and getting up late, resulting in disorder of the biological clock. An irregular body clock can lead to problems such as sleepiness and poor concentration. The survey found that more than 50 percent of people have irregular sleep and rest times.

4. Living habits and environmental factors

Some bad habits and environmental factors may also affect the quality of sleep. Excessive use of electronic devices, excessive caffeine intake, noise and light pollution can all interfere with people's sleep. These factors are prevalent in modern society and have a negative impact on people's sleep.

Second, how to improve sleep problems

1. Establish a regular sleep schedule: Try to go to bed and wake up at the same time every day to help adjust your body clock.

2. Create a comfortable sleeping environment: Keep your bedroom quiet, dark and cool, and use a comfortable mattress and pillow to provide a good sleeping environment.

3. Develop good bedtime habits: Avoid excessive use of electronic devices, avoid drinking caffeinated beverages before going to bed, and try to relax the body and mind, such as meditation, relaxing music, deep breathing, etc.

4. Regulate sleep with the help of corresponding supplements: such as NMN, melatonin, etc.

Third, how to choose NMN and melatonin

Sleep is a complex physiological process involving the interaction of multiple neurotransmitter systems and multiple networks of neurons that inhibit arousal and promote sleep. Short sleep duration and disturbed sleep can adversely affect metabolism and increase the risk of many chronic diseases, including obesity and type 2 diabetes.

1. Principle of action

Melatonin is a signal to promote sleep, in addition to melatonin, there are glycine, gamma-aminobutyric acid, glands and other substances, these substances will induce the body from waking to sleep conversion.

By increasing the content of NAD+ in the body, NMN regulates the circadian rhythm of the whole body to improve sleep by regulating PER2 sleep-related genes.

Melatonin, for example, is an external factor that creates a dark environment for the body by turning off the lights and drawing the curtains. NMN is the fundamental role of creating a dark night, allowing the body to work and rest regularly in the dark environment, and fundamentally solving sleep problems.

Therefore, melatonin is more suitable for people who need to be jet-lagged for short-term business trips, while NMN is generally suitable for people with sleep disorders, such as difficulty falling asleep, short sleep time, poor sleep quality and so on.

Step 2: Security

From the source of substances, melatonin and NMN are endogenous substances in the human body and will not be rejected by the body.

However, the amount of melatonin in the human body is small, only 0.1-0.3mg. Combined with current relevant studies, short-term use of small doses of melatonin is safe and has no obvious side effects. However, there are few studies on the safety of long-term melatonin use, and the conclusions are inconsistent.

According to China's "health food raw material catalog melatonin" recommended adult dosage is 1-3mg/d, while pointing out that it is not suitable for children, pregnant women, nursing mothers, and also stressed that engaged in driving, mechanical operations or dangerous operators, do not eat before or during operation. Use with caution in patients with autoimmune diseases (rheumatoid, etc.) and hyperthyroidism.

In recent years, more and more studies on NMN have been conducted, from animal trials to clinical trials, to verify the role and safety of NMN in many aspects. From the comprehensive data, it is safe for most people to ingestion 250-1000mg of NMN per day.

Third, the general conclusion

Good sleep is closely related to physical and mental health. Lack of sleep increases the risk of developing diseases such as heart disease, diabetes and depression, while getting enough sleep can improve physical and mental health and emotional stability. Existing studies have shown that NMN plays a fundamental role in improving sleep, which can effectively relieve sleep disorders and protect body health.