Long-term use of NMN may bring a range of potential benefits and effects, because of its subtle changes, it is difficult to notice in a short period of time, including but not limited to the following nine aspects.

1. Maintain a Healthy weight:

Research published in Scientific Reports indicates that NMN can regulate the metabolic state of fat cells by activating the "longevity protein" SIRT1, increasing energy expenditure, helping to maintain a healthy weight and reducing obesity problems.

2. Fatigue reduction:

NMN may help reduce fatigue by enhancing cellular energy supply and alleviating oxidative stress.

NAD+ is a key factor in intracellular energy metabolism, and NMN supplementation may increase cellular energy levels and reduce fatigue.

3. Improve memory:

By increasing the level of NAD+ in the brain, NMN helps to improve neuronal activity, improve memory and cognitive function, and slow the process of cognitive decline.

Ingestion of NMN may help prevent cognitive impairment and loss of hippocampal neurons, and NMN has great potential to maintain brain function and combat related complications.

4. Boost immunity:

NMN can enhance the activity of immune cells, improve the function of the immune system, enhance the body's resistance, and reduce the possibility of disease.

Studies have shown that NMN supplementation can increase the vitality and number of immune cells such as natural killer cells and lymphocytes, which is significant for fighting viruses, bacteria, and other pathogens.

5. Improve sleep:

A study published in Nutrients found that NMN plays a positive role in regulating melatonin levels, improving sleep quality in men, and promoting physical repair and recovery during sleep.

In the study on the effects of NMN intake on sleep quality, fatigue, and physical performance in older adults, the researchers divided 108 older participants into four groups (NMN premenstrual, NMN postmenstrual, placebo premenstrual, and placebo postmenstrual) and consumed 250 mg of NMN or placebo daily for 12 weeks.

The results of the study showed that compared with before taking NMN, the groups after taking NMN had significant improvement in physical fitness and sleep degree.

Ingested NMN effectively improved lower limb function and reduced fatigue in the elderly, resulting in better sleep.

6. Ease hair loss:

In a paper published in Molecules, NMN can inhibit DHT-induced inflammatory responses and oxidative stress by reducing ROS levels, increasing antioxidant enzyme activity, and inhibiting the activation of the NF-κB p65 inflammatory signaling pathway.

At the same time, NMN can also reduce the release of inflammatory factors and cell damage, promote the proliferation of hair follicle cells, enhance the supply of hair follicle nutrients, thereby promoting hair growth and reducing hair loss.

7. Improve skin condition:

NMN may improve skin elasticity and resistance by improving collagen synthesis and reducing oxidative stress.

NAD+ plays a role in cell repair and antioxidants, and NMN supplementation may help keep skin healthy.

Research published in ImmunoPharmacology International shows that topical use of NMN prevents eczema-like symptoms, including skin lesions, itching, rashes, and water loss, by blocking ROS.

In addition, NMN helps improve skin elasticity and moisture content by promoting collagen synthesis and increasing cellular energy production, reducing wrinkles and making skin younger and firmer.

8. Boost your energy:

The study found that NMN supplementation increases NAD+ levels and improves mitochondrial function, thereby enhancing energy production.

A study published in Aging Cell also showed that NMN helps improve exercise capacity and physical endurance.

9. Improve your focus:

NAD+ plays a role in maintaining nerve health and activating protein synthesis.

As a precursor of NAD+, NMN can enhance the level of intracellular NAD+, activate key proteins such as SIRT1 and SIRT2, promote cell energy production, DNA repair and antioxidant function, delay cell aging, improve the health of nerve cells, and make people more energetic.

In addition, NMN regulates gene expression, promotes mitochondrial function and cell signaling, improves cell quality and reduces inflammation, thereby protecting cells from damage, delaying aging, and improving overall health and quality of life.