In 2024, the Chinese Journal of Geriatrics released the Consensus of Clinical experts on Anti-Aging Drug Intervention Research in Chinese Geriatrics Medicine 2024, which was initiated by the Geriatric Medicine Branch of the Chinese Medical Association and jointly completed by experts and scholars involved in anti-aging drug intervention research among geriatrics experts in China, which mentioned that "NR and NMN are natural products. It is safe and can alleviate some degenerative diseases caused by aging."

Nicotinamide nucleoside (NR) and nicotinamide mononucleotide (NMN) are both natural products, and as precursors of NAD+, they have good safety in human studies. "Anti-aging Drug Intervention Research Chinese Geriatric Clinical expert Consensus 2024" clearly states that NAD+ supplements have the effect of anti-aging, and the release of the consensus marks an important breakthrough in the research of anti-aging drug intervention in the field of geriatric medicine in China.

As a coenzyme Ⅰ, NAD+ is widely present in all cells of the human body and plays an important role. NAD+ is a necessary coenzyme for life and cells, and participates in thousands of REDOX enzyme reactions in the human body. It can regulate the activity of cells, maintain normal life activities of the body, repair DNA, and play a decisive role in human aging. With the increase of age, NAD+ will gradually decline and lead to aging.

Consensus pointed out that through exogenous direct supplementation of NAD+, it can be rapidly absorbed and transported into cells with the help of CX43 channels, thereby activating the longevity protein Sirtuins and playing its specific physiological functions. This provides new possibilities for delaying aging and alleviating the degenerative diseases associated with it.